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Frozen shoulder syndrome, also known as adhesive capsulitis, is a debilitating condition characterized by pain and stiffness in the shoulder joint, leading to limited range of motion. Despite its high prevalence and impact on individuals, the molecular biology underlying limited shoulder motion in frozen shoulder syndrome remains poorly understood. This paper aims to provide an overview of the current knowledge regarding the molecular mechanisms involved in the pathogenesis of frozen shoulder syndrome. This paper also discusses the diagnostic and therapeutic implications of understanding the molecular biology of limited shoulder motion in frozen shoulder syndrome. Molecular markers for early diagnosis and prognosis could aid in identifying individuals at risk and guide treatment strategies. Targeted therapies based on the molecular mechanisms involved in frozen shoulder syndrome, including gene therapy and regenerative medicine approaches, show promise for future interventions. Despite recent advancements, several questions remain unanswered, and challenges persist in studying the molecular biology of frozen shoulder syndrome. Further research, interdisciplinary collaborations, and translational studies are needed to unravel the complexities of this condition and improve patient outcomes. Continued investigation into the molecular basis of limited shoulder motion in frozen shoulder syndrome holds significant potential for advancing our understanding and developing effective treatments for this debilitating condition.
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Hong Zhong, Jun Wang. Molecular Biology of Limited Shoulder Motion in Frozen Shoulder Syndrome. OAJRC Cellular and Molecular Biology, 2023, 5(1), 6-11.
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